Genetics Immuno


Medstudy Observations / General rules:
Male-to-male transmission eliminates X-linked and mitochondrial inheritance.
Transmission through 3 generations eliminates autosomal recessive inheritance.
Wiskott-Aldrich and Brutton Agammaglobulinemia are XLR = unlikely in a female w/ no family history.

Wiskott-Aldrich - XLR - "eczema-thrombocytopenia-immunodeficiency syndrome" 
Chronic granulomatous disease - X-linked - negative tetrazolium test - stem cell xplant to cure.
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