Hypertensive Urgency An SBP > 180 or DBP > 120 with no end-organ damage Herpertensive Emergency An increase in BP causing acute end-organ ischemia and damage. Pathophysiology Progression of essential hypertension. Progression of renovascular disease. Acute Glomerulonephritis Scleroderma Pre-Eclampsia Endo: Cushing's disease, Pheochromocytoma. Meds: Cocaine, Amphetamines, MAOi + tyramine. Treatment Monitor: UOP, Cr, mental status - deterioration my indicate higher GOAL BP. Hypertensive Emergency: Step 1: Within 2 hrs or faster if tolerate: Decrease MAP by 25% Step 2: In 2-6 hours attain a GOAL: DBP < 110 Hypertensive Urgency: Step 1: Within a few hours decrease BP with oral meds. Step 2: Attain GOAL: 1 - 2 days. IV Agents: Nitroprusside (*cyanide), Nitroglycerin, Labetolol, Hydralazine, Esmolol, Fenoldopam, Nicardipine, Phentolamine PO Agents: Captopril, Labetolol, Clonidine, Hydralazine Cerebral Injury: Treat BP only in the following circumstances: Thrombolysis, BP > 220/120, Ao dissection, Active ischemia, CHF Relevant Board Questions |