Complications - Ventilator Induced Lung Injury

Volutrauma - damage by "stretch", which incites inflammatory reaction
- Large tidal volume is an independent predictor of lung injury
 
Barotrauma - relates to mean and peak airway pressure (risk not independently associated with PEEP)
- pneumothorax
- pneumomediastinum
- subcutaneous emphysema
- pulmonary interstitial emphysema

Further classification:
- Macrobarotrauma
- Microbarotrauma
- Race (Rapid Alveolar Collapse and Expansion)
- O2 toxicity