Rheumatoid


Testing for which Hepatitis C should be done in pts with RA before initiating methotrexate? REF

The gout super primer CME question: REF


Sjögren’s syndrome is one of the three most common systemic autoimmune diseases. REF

What food decreases the risk of a gout attack ? REF

A meta-analysis of antidepressant medications for the treatment of fibromyalgia syndrome concluded that short-term use of amitriptyline and duloxetine can be considered for the treatment of pain and sleep disturbance in patients with fibromyalgia. REF

RA does not affect the lumber spine & any pt on a boards q w/ RA and lumber spine pain has another dx besides RA.  Medstudy Rheumatology Q9.

The 11 findings of SLE (4 required to diagnose).
1. anti-Sm Ab or antiphospholipid Ab
2. blood changes (anemia, leukopenia, etc).
3. photosensitivity
4. renal ds
5. +ANA, +anti-DsDNA Ab,  anti-Sm Ab 
6. arthritis
7. malar rash
8. discoid rash
9. neuropsychiatric features (psychosis, sz).
0. oral lesions
1. serositis


PMR never begins before the age of 60.
- usually starts around the shoulders
- stiff in the AM
- feel a little sick
- no specific joint problems
- mainly stiffness in shoulders and hips
- steroids relieve symptoms in 1 day

Dermatomyositis
- requires long-term steroid treatment

Steroids at 5 mg QD for greater than 3 months require a bisphosphonate.

Anti-histone antibodies
- drug-induced lupus
Anti-centromere antibodies
- CREST
Anti-SCL70
- Scleroderma
Anti-ds-DNA and anti-SM (less sensitive)
- Lupus (anti-ds-DNA correlates well with renal involvement)
ANA
- Raynaud's Disease
anti-RNP
- mixed connective tissue disease
SS-A(Ro)
- neonatal lupus, Sjogren syndrome, systemic sclerosis
cANCA
- Wegener's granulomatosis
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